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OEM China Hydroxylammonium Chloride - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu Featured Image
  • OEM China Hydroxylammonium Chloride - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu

OEM China Hydroxylammonium Chloride - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu

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OEM China Hydroxylammonium Chloride - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu Detail:

Manufacturer Supply High Quality, Commercial Production
Chemical Name: 2-Methyl-4-Nitrobenzoic Acid
CAS: 1975-51-5

Chemical Name 2-Methyl-4-Nitrobenzoic Acid
Synonyms 4-Nitro-o-Toluic Acid; 4-Nitro-2-Methylbenzoic Acid
CAS Number 1975-51-5
CAT Number RF-PI397
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H7NO4
Molecular Weight 181.15
Brand Ruifu Chemical
Item Specifications
Appearance Almost White or Pale Yellow Crystal Powder
1H-NMR Consistent with Structure
Purity / Analysis Method ≥98.0% (HPLC)
Melting Point 153.0~156.0℃
Moisture (K.F) ≤0.50%
Residue on Ignition ≤0.50%
Total Impurities ≤2.0%
Test Standard Enterprise Standard
Usage Intermediate of Tolvaptan (CAS 150683-30-0)

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

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2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) is used as a pharmaceutical intermediate in the synthesis of Tolvaptan (CAS 150683-30-0). Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. Tolvaptan is used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan was approved by the U.S. Food and Drug Administration on May 19, 2009, and is sold by Otsuka Pharmaceutical Co. under the trade name Samsca.

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