OEM Factory for L-(-)-DBTA·H2O - (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity – Ruifu
OEM Factory for L-(-)-DBTA·H2O - (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity – Ruifu Detail:
Manufacturer Supply Atazanavir Related Intermediates
Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
| Chemical Name | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| Synonyms | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane; (2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane; Darunavir Intermediate |
| CAS Number | 98737-29-2 |
| CAT Number | RF-PI286 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C15H21NO3 |
| Molecular Weight | 263.33 |
| Solubility | Insoluble in Water. Soluble in Methanol, Chloroform |
| Shipping Condition | Shipped Under Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Identification (HPLC) | The Identification is Confirmed by HPLC |
| Melting Point | 123.0~128.0℃ |
| Moisture (K.F) | ≤0.50% |
| Residue on Ignition | ≤0.20% |
| Purity / Analysis Method | ≥99.0% (HPLC) |
| Chlorohydrin (HPLC) | ≤0.20% |
| Chloromethyl Ketone | ≤0.10% |
| Other Single Impurity | ≤0.20% |
| Total Impurities | ≤1.0% |
| Chiral Impurity | ≤0.30% |
| Heavy Metals | ≤20ppm |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) with high quality, an intermediate typically in the synthesis of Atazanavir (CAS 198904-31-3) and Atazanavir Sulfate (CAS 229975-97-7).
Atazanavir is a highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC 50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.
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