OEM Manufacturer Bestatin - Caspofungin Acetate Cancidas CAS 179463-17-3 API High Purity – Ruifu
OEM Manufacturer Bestatin - Caspofungin Acetate Cancidas CAS 179463-17-3 API High Purity – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Chemical Name: Caspofungin Acetate
Synonyms: MK-0991 Acetate; L-743872 Acetate
CAS: 179463-17-3
The first inhibitor of fungal β-1,3 glucan synthase; Antifungal agent
API High Quality, Commercial Production
Chemical Name | Caspofungin Acetate |
Synonyms | MK-0991 Acetate; L-743872 Acetate |
CAS Number | 179463-17-3 |
CAT Number | RF-API58 |
Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
Molecular Formula | C52H88N10O15·2C2H4O2 |
Molecular Weight | 1213.42 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Off-White Crystalline Powder |
Identification | by IR and HPLC, Conforms |
Clarity and Color | Comply with Requirements |
Specific Rotation | -102.0° ~ -108.0° |
Single Max. Impurity | ≤0.50% |
Total impurities | ≤1.0% |
Heavy Metals | ≤10ppm |
Loss on Ddrying | ≤1.0% |
Residual on Ignition | ≤0.10% |
Assay / Analysis Method | ≥97.0% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Caspofungin Acetate (CAS: 179463-17-3) with high quality.
Caspofungin Acetate (CAS: 179463-17-3) is the first in a new class of antifungal agents named echinocandin to be launched in the US for the parenteral treatment of invasive aspergillosis in patients refractory to, or intolerant of other antifungal therapies such as amphotericin-B1 lipid formulation of amphotericin-B and/or itraconazole. Caspofungin Acetate (CAS: 179463-17-3) is a water soluble, stable, aza-substituted semisynthetic derivative of pneumocandin B, a fermentation product of the fungus Zalerion arboricola. Since fungi and humans are both eukaryotes, new antifungal agents must focus on fungus-specific targets in order to minimize potential toxicity in the human host. In this respect, the lipopeptide caspofungin, inhibits the synthesis of 1,3-beta- D-glucans present only in the fungal cell wall, which leads to the specific lysis of the pathogenic cells. The compound is fungicidal rather than fungistatic, an unusual feature among antifungal agents. Caspofungin has activity in vitro and in vivo against a range of Candida species (including azole and amphotericin B resistant Candida) and also against Aspergillus, an important pathogen which is not susceptible to fluconazole. Caspofungin was generally more active than amphotericin B, flucytosine, fluconazole and itraconazole against Candida species. Cryptococcus is not susceptible to caspofungin. Caspofungin has a half-life in human beings around 10 hours. Unlike the azoles, caspofungin does not inhibit cytochrome P450. The drug has been given intravenously with loading dose of 70 rag, followed by 50 mg daily to be effective in invasive aspergillosis refractory to prior antifungal therapy. Most of the side effects were mild and comprised fever, thrombophlebitis, headache, nausea, rash and flushing.
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We have a professional, efficiency team to provide quality service for our customer. We always follow the tenet of customer-oriented, details-focused for OEM Manufacturer Bestatin - Caspofungin Acetate Cancidas CAS 179463-17-3 API High Purity – Ruifu , The product will supply to all over the world, such as: Malawi, Czech, Bahrain, We solution have passed through the national skilled certification and been well received in our key industry. Our specialist engineering team will often be ready to serve you for consultation and feedback. We've been able to also provide you with no cost samples to meet your needs. Best efforts are going to be produced to supply you the very best service and solutions. For anyone who is considering our business and solutions, please speak to us by sending us emails or get in touch with us right away. As a way to know our items and enterprise. lot more, you'll be able to come to our factory to find out it. We'll constantly welcome guests from around the globe to our firm. o build enterprise. elations with us. You should really feel absolutely free to make contact with us for small business and we believe we'll share the top trading practical experience with all our merchants.
By ron gravatt from Mexico - 2018.05.15 10:52
This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
By Lesley from Bolivia - 2018.06.05 13:10