OEM Manufacturer (S)-(+)-Glycidyl Phthalimide - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu

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OEM Manufacturer (S)-(+)-Glycidyl Phthalimide - 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality – Ruifu Detail:

Manufacturer Supply High Quality, Commercial Production
Chemical Name: 2-Methyl-4-Nitrobenzoic Acid
CAS: 1975-51-5

Chemical Name	2-Methyl-4-Nitrobenzoic Acid
Synonyms	4-Nitro-o-Toluic Acid; 4-Nitro-2-Methylbenzoic Acid
CAS Number	1975-51-5
CAT Number	RF-PI397
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C8H7NO4
Molecular Weight	181.15
Brand	Ruifu Chemical

Item	Specifications
Appearance	Almost White or Pale Yellow Crystal Powder
1H-NMR	Consistent with Structure
Purity / Analysis Method	≥98.0% (HPLC)
Melting Point	153.0~156.0℃
Moisture (K.F)	≤0.50%
Residue on Ignition	≤0.50%
Total Impurities	≤2.0%
Test Standard	Enterprise Standard
Usage	Intermediate of Tolvaptan (CAS 150683-30-0)

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) is used as a pharmaceutical intermediate in the synthesis of Tolvaptan (CAS 150683-30-0). Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. Tolvaptan is used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan was approved by the U.S. Food and Drug Administration on May 19, 2009, and is sold by Otsuka Pharmaceutical Co. under the trade name Samsca.

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