OEM/ODM Manufacturer Glioblastoma Multiforme - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu

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OEM/ODM Manufacturer Glioblastoma Multiforme - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu Detail:

Supply Vonoprazan Fumarate and Related Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2

Chemical Name Vonoprazan Fumarate
Synonyms TAK-438
CAS Number 1260141-27-2; 881681-01-2
CAT Number RF-API99
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C21H20FN3O6S
Molecular Weight 461.463
Brand Ruifu Chemical
Item Specifications
Appearance White or Almost-White Crystalline Powder
Identification 1 H-NMR Consistent with the Standard
Identification IR The IR Absorption spectrum of the sample concordant with reference standard
Identification HPLC The retention time of the sample concordant with reference standard
Related Substances
Impurity A ≤0.20%
Impurity B ≤0.15%
Impurity C ≤0.15%
Any Other Impurity ≤0.10%
Total Impurities ≤1.0%
Residual Solvents
Methanol ≤0.30%
Ethanol ≤0.50%
Ethyl Acetate ≤0.50%
Assay / Analysis Method 98.0%~102.0% (By HPLC)
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

1

Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate (Takecab), discovered and developed by Takeda and Otsuka, was approved by the PMDA of Japan in December 2014. Vonoprazan Fumarate is mainly used for the treatment of helicobacter pylori infection, gastroesophageal reflux, peptic ulcer, duodenal ulcer, esophagitis, gastric ulcer and other gastric acid related diseases. The product has a strong, lasting inhibition of gastric acid secretion. At the treatment dose, Vonoprazan Fumarate has little effect on other enzymes and little effect on physiological functions of the body. It is safe and more tolerable.


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Persisting in "High quality, Prompt Delivery, Aggressive Price", now we have established long-term cooperation with consumers from equally overseas and domestically and get new and old clients' large comments for OEM/ODM Manufacturer Glioblastoma Multiforme - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu , The product will supply to all over the world, such as: Victoria, Greek, Curacao, Our company has already had a lot of top factories and qualified technology teams in China, offering the best goods, techniques and services to worldwide customers. Honesty is our principle, skilled operation is our work, service is our goal, and customers' satisfaction is our future!
  • We feel easy to cooperate with this company, the supplier is very responsible, thanks.There will be more in-depth cooperation.
    5 Stars By Teresa from Turkey - 2018.10.01 14:14
    This manufacturer can keep improving and perfecting products and service, it is in line with the rules of market competition, a competitive company.
    5 Stars By Frederica from Comoros - 2017.08.18 11:04
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