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One of Hottest for Ropivacaine HCl.H2O - Ropivacaine Hydrochloride Monohydrate CAS 132112-35-7 API USP Standard High Purity – Ruifu

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One of Hottest for Ropivacaine HCl.H2O - Ropivacaine Hydrochloride Monohydrate CAS 132112-35-7 API USP Standard High Purity – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Chemical Name: Ropivacaine Hydrochloride Monohydrate
Synonyms: Ropivacaine HCl.H2O
CAS: 132112-35-7  
An anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly
API USP Standard, High Quality, Commercial Production

Chemical Name Ropivacaine Hydrochloride Monohydrate
Synonyms Ropivacaine HCl.H2O
CAS Number 132112-35-7
CAT Number RF-API42
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C17H26N2O.ClH.H2O
Molecular Weight 328.88
Brand Ruifu Chemical
Item Specifications
Appearance White Powder
Identification (1) It should be positive reaction 
(2) IR: Meets the requirement 
Color The absorbance at 405nm is not more than 0.030 
The absorbance at 436nm is not more than 0.025 
pH 4.5~6.0
Related Substances  
Total Impurity ≤0.50%
Single Impurity ≤0.10%
Bupivacaine ≤0.20%
Optical Isomers ≤0.50%
Water 5.0%~6.0%
Heavy Metals ≤10ppm
2,6-Dimethylaniline ≤10ppm
Specific Rotation Obtain readings at 365 nm: between -210° ~ -255° 
Assay 98.5%~101.0%
Test Standard United States Pharmacopeia (USP) Standard
Usage Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Ropivacaine Hydrochloride Monohydrate (CAS: 132112-35-7) with high quality.

Ropivacaine hydrochloride monohydrate is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly. Ropivacaine is a long-acting amide local anaesthetic agent and first produced as a pure enantiomer. It produces effects similar to other local anaesthetics via reversible inhibition of sodium ion influx in nerve fibres. Ropivacaine is less lipophilic than bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity. The drug displays linear and dose proportional pharmacokinetics (up to 80 mg administered intravenously). It is metabolised extensively in the liver and excreted in urine. The present article details the clinical applications of ropivacaine and its current place as a local anaesthetic in the group.

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