One of Hottest for Ropivacaine HCl.H2O - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API High Quality – Ruifu

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One of Hottest for Ropivacaine HCl.H2O - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API High Quality – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6

Chemical Name	Sorafenib Tosylate
CAS Number	475207-59-1
CAT Number	RF-API05
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C28H24ClF3N4O6S
Molecular Weight	637.03
Brand	Ruifu Chemical

Item	Specifications
Appearance	Light Yellow or White Powder
Purity / Analysis Method	≥99.0% (HPLC)
Melting Point	225.0~235.0℃
Heavy Metals	≤10ppm
Loss on Drying	≤0.5%
Test Standard	Enterprise Standard
Usage	Sorafenib Tosylate (CAS: 475207-59-1) in the treatment of RCC & HCC

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

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