Original Factory Uracil 1-β-D-Arabinofuranoside - 2′-Deoxycytidine CAS 951-77-9 Purity ≥99.0% (HPLC) High Purity – Ruifu

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Original Factory Uracil 1-β-D-Arabinofuranoside - 2′-Deoxycytidine CAS 951-77-9 Purity ≥99.0% (HPLC) High Purity – Ruifu Detail:

Manufacturer Supply Deoxynucleosides Intermediates with High Purity and Stable Quality

2′-Deoxyguanosine monohydrate CAS: 961-07-9	2′-Deoxyadenosine CAS: 958-09-8
2′-Deoxyuridine CAS: 951-78-0	2′-Deoxycytidine CAS: 951-77-9
5-Iodo-2′-Deoxyuridine CAS: 54-42-2

Chemical Name	2′-Deoxycytidine
CAS Number	951-77-9
CAT Number	RF-PI206
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C9H13N3O4
Molecular Weight	227.22
Brand	Ruifu Chemical

Item	Specifications
Appearance	White or Almost White Crystalline Powder
Heavy Metals	≤20ppm
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Purity / Analysis Method	≥99.0% (HPLC)
Test Standard	Enterprise Standard

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

2-Deoxycytidine is a cytidine analog. 2′-Deoxycytidine is a deoxyribonucleoside as Eg5 kinesin modulator with apoptosis-inducing and antiproliferative activity.

2-Deoxycytidine prevents DNA methylation by incorporating itself into newly synthesizing DNA strand. 2-Deoxycytidine also binds to DNA methyltransferase irreversibly and hinders its activity. Thus, 2-deoxycytidine was approved as the most efective demethylating agent for the treatment of cancer .

2-Deoxycytidine at clinically achievable and nontoxic concentrations (≥ 100 μmol/L) protected normal bone marrow progenitor cells against the inhibitory effects of co-administered, high concentrations of 3’-azido-3’-deoxythymidine (AZT) (≥ 10 μmol/L). In normal bone marrow mononuclear cells (BMMC), 2-deoxycytidine also significantly corrected AZT-mediated depletion of intracellular thymidine triphosphate and 2-deoxycytidine triphosphate levels. Furthermore, 2-deoxycytidine reduced the intracellular accumulation of AZT triphosphate and its DNA incorporation in BMMC.

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