Palbociclib Intermediate II CAS 1013916-37-4 Purity >98.0% (HPLC) Factory High Quality
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
| Chemical Name | 2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one |
| Synonyms | 2-Chloro-8-Cyclopentyl-5-Methylpyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Intermediate 2; Palbociclib Intermediate II; Palbociclib Impurity 48 |
| CAS Number | 1013916-37-4 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C13H14ClN3O |
| Molecular Weight | 263.72 |
| Density | 1.346±0.06 g/cm3 (Predicted) |
| Melting Point | 176.0-178.0℃ |
| Water Solubility | Slightly Soluble in Water |
| Storage Condition | Under Inert Gas (Nitrogen or Argon) at 2-8℃ |
| Shipping Conditions | Shipped Under Ambient Temperature |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories | Palbociclib Intermediates |
| Brand | Ruifu Chemical |
| Item | Specifications | Results |
| Appearance | Light Yellow to Brownish Yellow Powder | Light Yellow Powder |
| Water (K.F) | <0.50% | 0.10% |
| Related Substances | ||
| Intermediate I | <0.50% | 0.06% |
| Any Other Individual Impurity | <0.30% | 0.23% |
| Purity / Analysis Method | >98.0% (HPLC) | 99.52% |
| Test Standard | Enterprise Standard | Conforms |
| Application | Intermediate of Palbociclib (CAS: 571190-30-2) | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS: 1013916-37-4) is used as a pharmaceutical intermediate of Palbociclib (CAS: 571190-30-2).
Palbociclib is a drug for the treatment of ER-positive and HER2-negative breast cancer developed. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy by any organization, and as of December 2017 has been prescribed more than 90,000 times.
-
Palbociclib Intermediate II CAS 1013916-37-4 Pu...
-
Palbociclib CAS 571190-30-2 Purity >99.5% (HPLC...
-
Palbociclib Intermediate CAS 1016636-76-2 Purit...
-
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Ca...
-
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-...
-
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5 P...
-
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine...