Perindopril Erbumine CAS 107133-36-8 Purity >99.5% (HPLC) ACE Inhibitor API Factory High Quality

Short Description:

Chemical Name: Perindopril Erbumine 

CAS: 107133-36-8

Purity: >99.5% (HPLC)

Appearance: White to Off-White Crystalline Powder 

Perindopril Erbumine is a Potent ACE Inhibitor

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name Perindopril Erbumine
Synonyms Perindopril tert-Butylamine Salt; Aceon; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt
CAS Number 107133-36-8
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C19H32N2O5.C4H11N
Molecular Weight 441.61
Melting Point 126.0~128.0℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Off-White Crystalline Powder
Identification IR; HPLC
Specific Rotation [α]D20 -66.0°~-69.0°  
Impurities A ≤0.25%
Impurities I ≤0.10%
Unknown Impurities ≤0.10%
Impurities E ≤0.40%
Impurities B ≤0.30%
Impurities F ≤0.20%
Impurities H  ≤0.20%
Unknown Impurities ≤0.10% 
Total Impurities <0.50%
Water Content ≤1.00%
Residue on Ignition ≤0.10%
Heavy Metals ≤20ppm
Purity / Analysis Method >99.5% (HPLC)
Related Substances Meet the Specification
Test Standard Enterprise Standard
Usage API; ACE Inhibitor; Antihypertensive

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

1

FAQ:

Application:

Perindopril Erbumine (CAS: 107133-36-8), also known as Perindopril tert-Butylamine Salt, is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. Inhibition of this enzyme prevents the formation of angiotensin II from angiotensin I, which in turn prevents vasoconstriction caused by angiotensin II. Perindopril Erbumine is an orally bioavailable long acting angiotensin converting enzyme (ACE) inhibitor (IC50 value of 10 μM). Specifically, Perindopril Erbumine is an oral prodrug of Perindoprilat, a potent ACE inhibitor with an IC50 value of 1.9 nM.

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