Posaconazole Intermediate CAS 170985-85-0 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde

Short Description:

Chemical Name: 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde

CAS: 170985-85-0

Appearance: White or Off-White Powder

Purity: ≥98.0% (HPLC)

Intermediate of Posaconazole (CAS 171228-49-2) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde
Synonyms N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide; N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide; Posaconazole Intermediate; Posaconazole Impurity 33 
CAS Number 170985-85-0
CAT Number RF-PI292
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C13H20N2O2
Molecular Weight 236.31
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Off-White Powder
Identification  H-NMR: Conforms to the Standard
Loss on Drying ≤0.50%
Purity / Analysis Method ≥98.0% (HPLC)
Organic Impurities
Any Single Impurity ≤0.50%
Total Organic Impurities ≤2.0%
Heavy Metals ≤20ppm
Test Standard Enterprise Standard
Usage Intermediate of Posaconazole (CAS 171228-49-2) Antifungal Agent

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

2-[(1S,2S)-1-Ethyl-2-(Phenylmethoxy)propyl]hydrazinecarboxaldehyde (CAS: 170985-85-0) is an important intermediate of Posaconazole (CAS 171228-49-2). Posaconazole is a triazole antifungal drug widely used in the treatment of invasive infections. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Posaconazole is derived from itraconazole. Its pharmacological effects are similar with azoles, but compared with Itraconazole, it has a stronger inhibitory effect on the C14 demethylation of steroid, especially for Aspergillus. Posaconazole, launched in the UK, is the newest member of the azole class of antifungal agents to reach the market.  

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