Prostaglandin E1 (Alprostadil; PGE1) CAS 745-65-3 Assay 95.0~102.5%

Prostaglandin E1 (Alprostadil; PGE1) (CAS: 745-65-3) is a biologically active substance widely present in the body. It is a member of the prostaglandin family and is recognized as an endogenous physiologically active substance. Prostaglandin E1 acts directly on vascular smooth muscle, dilates blood vessels, increases blood flow, improves microcirculation perfusion, inhibits platelet aggregation and thromboxane A2 production, and inhibits atherosclerosis, lipid plaque and immune complex formation; dilate peripheral small vessels and coronary arteries, reduce peripheral vascular resistance and blood pressure, protect platelet membrane, prevent thrombosis; Protect ischemic myocardium, reduce myocardial infarction area; Anti-heart failure; Dilate renal vessels, increases renal blood flow, removes non-protein nitrogen, regulates water-sodium balance, has a diuretic and protective effect on renal function.
Used for diabetic neuropathy, myocardial infarction, thrombotic vasculitis, arteriosclerosis obliterans, central retinal vein thrombosis. It is used in the treatment of hepatitis cirrhosis, cerebral infarction, diabetes, impotence, respiratory diseases. Liver damage is not serious childA, class B patients, especially patients with antithrombin level childA China effect. For induction of labor, oxytocin, renal insufficiency, treatment mumps, pancreatitis. Injection of Prostaglandin E1 is mainly applied to myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusive disease, central retinal vein thrombosis, platelet protection for extracorporeal circulation, arteriography, revascularization surgery.