Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 COVID-19
Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality
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Chemical Name | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)tetrahydrofuran-2-Carbonitrile |
Synonyms | GS-441524; Remdesivir Metabolite; Remdesivir Intermediate; Nucleosid of Remdesivir; EVO984; Remdesivir O-Desphosphate Analogue; Remdesivir Related Compound 6 Impurity |
CAS Number | 1191237-69-0 |
CAT Number | RF-PI299 |
Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
Molecular Formula | C12H13N5O4 |
Molecular Weight | 291.26 |
Solubility | Soluble in DMSO |
Storag | Cool Dry Place |
Shipping Condition | Shipped Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Almost White Powder |
Purity | ≥99.0% |
Alpha-Isomer | ≤0.30% |
O-Bn Derivative | ≤0.30% |
N-Bn Derivative | ≤0.30% |
Maximum Single Impurity | ≤0.30% |
Loss on Drying | ≤1.0% |
Residue on Ignition | ≤0.50% |
Heavy Metals | ≤20ppm |
Arsenic | ≤2ppm |
Test Standard | Enterprise Standard |
Usage | Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19 |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.