Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3 Purity >99.0% (HPLC) Factory High Quality

Short Description:

Chemical Name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 486460-21-3

Purity: >99.0% (HPLC)

Appearance: White to Light Yellow Powder

Intermediate of Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) for the treatment of type II diabetes mellitus

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Product Detail

Product Tags

Description:

Supply Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Chemical Properties:

Chemical Name	3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride
Synonyms	Sitagliptin Phosphate Monohydrate Intermediate
CAS Number	486460-21-3
CAT Number	RF-PI1194
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C6H7F3N4
Molecular Weight	192.14
Boiling Point	266℃
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Light Yellow Powder
Identification	The UV absorption spectrum of the standard sample exhibits maximum＆minimum at same wavelengths
Identification	HPLC: Retention time Similar
Loss on Drying	<2.00%
Ordinary Impurities	<1.00%
Purity / Analysis Method	>99.0% (HPLC)
Test Standard	Enterprise Standard
Usage	Intermediate of Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

FAQ:

Application:

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 486460-21-3) is an intermediate of Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) for the treatment of type II diabetes mellitus. Sitagliptin is approved by the FDA as an adjunct to diet and exercise to improve glycaemic control in patients with T2DM, either as a monotherapy, or in combination with Metformin or a peroxisome proliferatoractivated receptor-γ agonist (for example, thiazolidinediones) when the single agent does not provide adequate glycaemic control.