Super Lowest Price 4-Acetamidophenol - Sitagliptin CAS 486460-32-6 Purity >99.0% (HPLC) API Factory High Purity – Ruifu
Super Lowest Price 4-Acetamidophenol - Sitagliptin CAS 486460-32-6 Purity >99.0% (HPLC) API Factory High Purity – Ruifu Detail:
Manufacturer Supply With High Quality, Commercial Production
Chemical Name: Sitagliptin CAS: 486460-32-6
| Chemical Name | Sitagliptin |
| Synonyms | (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one |
| CAS Number | 486460-32-6 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | 407.31 |
| Melting Point | 114.0~115.0℃ |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Identification by HPLC | The Retention Time of Sample is Concordant With Reference Standard |
| Loss on Drying | <1.0% |
| Residue on Ignition | <0.20% |
| Related Substances | |
| Any Single Impurity | <0.50% |
| Total Impurities | <1.0% |
| Purity | >99.0% (HPLC) |
| Enantiomeric Purity | <0.50% |
| Heavy Metals | <20ppm |
| Test Standard | Enterprise Standard |
| Usage | API; Type II Diabetes Mellitus |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Sitagliptin (CAS: 486460-32-6), as a new type of antidiabetic drug, Sitagliptin Phosphate has the advantages of glucose dependence, moderate hypoglycemic effect, increased secretion without hypoglycemia, effectively alleviated hunger, and had no side effects such as nausea, vomiting, edema and increased body weight. Sitagliptin phosphate as a single drug treatment in patients with type II diabetes can significantly reduce the level of glycosylated hemoglobin (HbA1c). It is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which can improve the human body’s ability to reduce high blood glucose level. Sitagliptin was developed by Merck & Co. and approved for medical use in the United States in 2006.
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