Trityl Olmesartan Medoxomil CAS 144690-92-6 Purity >99.0% (HPLC) Olmesartan Medoxomil Intermediate Factory

Short Description:

Chemical Name: Trityl Olmesartan Medoxomil 

CAS: 144690-92-6

Purity: >99.0% (HPLC)  

Appearance: White to Off-White Powder

Intermediate of Olmesartan Medoxomil 

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name Trityl Olmesartan Medoxomil
Synonyms Tritylolmesartan Medoxomil; Triphenyl Methyl Olmesartan; N1-Trityl Olmesartan Medoxomil; Olmesartan Medoxomil EP Impurity D; Olmesartan USP Impurity D; Olmesartan Medoxomil-4; 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-[2-(Triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-Imidazole-5-Carboxylate
CAS Number 144690-92-6
CAT Number RF-PI1874
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C48H44N6O6
Molecular Weight 800.90
Melting Point 104.0~106.0℃
Density 1.26±0.10 g/cm3
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder 
Identification HPLC; NMR; LC-MS
Purity / Analysis Method >99.0% (HPLC)
Water (K.F) <0.50%
Residue on Ignition <0.10%
Related Substances
Individual Impurity <0.50%
Total Impurities <1.00%
Heavy Metals <10ppm
Test Standard Enterprise Standard
Usage Intermediate of Olmesartan Medoxomil (CAS: 144689-63-4)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

Trityl Olmesartan Medoxomil (CAS: 144690-92-6) is a key intermediate used in the preparation of Olmesartan Medoxomil (CAS: 144689-63-4), an angiotension II receptor antagonist, used in the treatment of hypertension. Olmesartan Medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM. Olmesartan Medoxomil, a prodrug of Olmesartan, is an angiotensin II type 1 receptor (AT1) inhibitor that inhibits negative regulatory feedback on renin secretion, decreasing secretion of aldosterone and resulting in decreased peripheral vascular resistance (vasodilation). It may be used alone or in combination with other antihypertensive agents.

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