Vidarabine (Ara-A) CAS 5536-17-4 Purity≥99.0% (HPLC) Factory High Quality

Short Description:

Chemical Name: Vidarabine

Synonyms: Ara-A; Arabinoadenosine

CAS: 5536-17-4

Appearance: White or Off-White Crystalline Powder

Purity: ≥99.0% (HPLC)

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply Arabinonucleosides Intermediates with High Purity
Vidarabine; Ara-A; CAS: 5536-17-4
Arabinofuranosyluracil; Ara-U ; CAS: 3083-77-0
Cytarabine; Ara-C; CAS: 147-94-4

Chemical Properties:

Chemical Name	Vidarabine
Synonyms	Ara-A; Arabinoadenosine; Adenine 9-β-D-Arabinofuranoside; Vira-A
CAS Number	5536-17-4
CAT Number	RF-PI220
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C10H13N5O4
Molecular Weight	267.25
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Solubility	Colorless Clear
Purity / Analysis Method	≥99.0% (HPLC)
UV Content	≥98% (on Dry Basis)
Specific Rotation [a]D20	-56.0°～-65.0° (C=1 in DMF)
Adenine	≤0.50%
Adenosine	≤0.50%
Ara-U	≤0.50%
Melting Point	260.0~265.0℃
Heavy Metals	≤20ppm
Test Standard	Enterprise Standard
Storage Temperature	Store at 0~8℃
Usage	API; Pharmaceutical Intermediates

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Vidarabine (CAS: 5536-17-4), is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Vidarabine (CAS: 5536-17-4) is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine (CAS: 5536-17-4) is an inhibitor of A cyclase and DNA Polymerase. Adenine 9-beta-D-arabinofuranoside (ara-A) is a synthetically produced purine nucleoside that is used in cell signaling research. It has commonly been used in anti-viral research with hepadnaviridae and herpes simplex viruses. The nucleoside ara-A interferes with viral DNA synthesis, but only in its active phosphorylated form.

Vidarabine (CAS: 5536-17-4) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus. Vidarabine (CAS: 5536-17-4) is capable of inhibiting acyclovir-resistant/TK-deficient mutants of HSV and VZV, because it is phosphorylated to its active vidarabine–triphosphate form by cellular kinases and is not dependent for its activation on the viral TK.